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Bioorg Med Chem Lett. 2003 Jun 16;13(12):2079-82.

Urea small molecule agonists on mouse melanocortin receptors.

Author information

1
Department of Medicinal Chemistry, University of Florida, PO Box 100485, Gainesville, FL 32610, USA.

Abstract

A series of urea compounds based on the tripeptide Phe-Trp-Lys were synthesized and pharmacologically characterized at the mouse melanocortin receptors. The results include identification of novel melanocortin receptor agonists with potencies ranging from nanomolar to micromolar.

PMID:
12781199
DOI:
10.1016/s0960-894x(03)00318-4
[Indexed for MEDLINE]

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