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Contact Dermatitis. 2003 Mar;48(3):155-7.

Airborne allergic contact dermatitis from 3-iodo-2-propynyl-butylcarbamate at a paint factory.

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  • 1Department of Dermatology, Odense University Hospital, University of Southern Denmark and National Allergy Research Centre, Gentofte, Denmark.


3-Iodo-2-propynyl-butylcarbamate (IPBC) is a fungicide used in both industrial products and cosmetics. We report the first case of allergic contact dermatitis from airborne exposure to this preservative. A 34-year-old female production worker at a paint factory developed dermatitis on air-exposed skin areas. Patch testing showed a ++ reaction to the preservative IPBC 0.01% in petrolatum. The compound was used as a preservative in wood treatment products manufactured at her work place. Based on animal studies, IPBC is considered safe as a cosmetic preservative. However, widespread use of the chemical might lead to increasing levels of contact allergy, and therefore, close monitoring of IPBC is recommended.

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