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Int J Med Microbiol. 2003 Apr;293(1):17-39.

Intestinal M cells and their role in bacterial infection.

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  • 1Department of Physiological Sciences, University of Newcastle, Newcastle upon Tyne NE2 4HH, UK.

Abstract

M cells are located in the epithelia overlying mucosa-associated lymphoid tissues such as Peyer's patches where they function as the antigen sampling cells of the mucosal immune system. Paradoxically, some pathogens exploit M cells as a route of invasion. Here we review our current knowledge of intestinal M cells with particular emphasis on the mechanisms underlying bacterial infection of these atypical epithelial cells.

PMID:
12755364
DOI:
10.1078/1438-4221-00242
[PubMed - indexed for MEDLINE]
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