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Infect Dis Clin North Am. 2003 Mar;17(1):159-91, ix.

Clinical pharmacology of antifungal compounds.

Author information

1
Infectious Disease Research Program, Center for Bone Marrow Transplantation, Department of Pediatric Hematology/Oncology, Wilhelms-University Medical Center, Domagkstrasse 9a, 48149 Muenster, Germany. grollan@mednet.uni-muenster.de

Abstract

Prompted by the worldwide surge in fungal infections, the past decade has witnessed a considerable expansion in antifungal drug research. New compounds have entered the clinical arena, and major progress has been made in defining paradigms of antifungal therapies. This article provides an up-to-date review on the clinical pharmacology, indications, and dosage recommendations of approved and currently investigational therapeutics for treatment of invasive fungal infections in adult and pediatric patients.

PMID:
12751265
DOI:
10.1016/s0891-5520(02)00068-5
[Indexed for MEDLINE]

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