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Clin Infect Dis. 2003 May 15;36(10):1290-4. Epub 2003 May 8.

Topical microbicides for disease prevention: status and challenges.

Author information

1
Alliance for Microbicide Development, Silver Spring, Maryland 20910, USA. pharrison@microbicide.org

Abstract

As the human immunodeficiency virus and sexually transmitted disease epidemics advance relentlessly, it is clear that an armamentarium of therapeutic and preventive methods will be essential to their containment. Topical microbicides--self-administered prophylactic agents applied to the vagina or rectum in various formulations--could be a crucial addition to that necessary armamentarium. This article provides an update on the dramatically broadening array of approaches being pursued in microbicide research and development and identifies critical challenges to progress.

PMID:
12746775
DOI:
10.1086/374834
[Indexed for MEDLINE]

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