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Appl Microbiol Biotechnol. 2003 May;61(4):269-77. Epub 2003 Mar 15.

Biotransformation of limonene by bacteria, fungi, yeasts, and plants.

Author information

1
Institute of Biotechnology, ETH Hönggerberg, HPT, 8093 Zürich, Switzerland. duetz@enzyscreen.com

Abstract

The past 5 years have seen significant progress in the field of limonene biotransformation, especially with regard to the regiospecificity of microbial biocatalysts. Whereas earlier only regiospecific biocatalysts for the 1,2 position (limonene-1,2-diol) and the 8-position (alpha-terpineol) were available, recent reports describe microbial biocatalysts specifically hydroxylating the 3-position (isopiperitenol), 6-position (carveol and carvone), and 7-position (perillyl alcohol, perillylaaldehyde, and perillic acid). The present review also includes the considerable progress made in the characterization of plant P-450 limonene hydroxylases and the cloning of the encoding genes.

PMID:
12743755
DOI:
10.1007/s00253-003-1221-y
[Indexed for MEDLINE]

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