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Microbes Infect. 2003 Apr;5(5):419-27.

Trypanosoma cruzi clonal diversity and the epidemiology of Chagas' disease.

Author information

1
Michael Heidelberg Division of Immunology, Department of Pathology, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA. busac01@med.nyu.edu

Abstract

Chagas' disease is caused by the protozoan Trypanosoma cruzi and it has a variable clinical outcome. The basis for this variability relies in part on the complexity of the parasite population consisting of multiple clones displaying distinct biological properties. A major current challenge is to correlate parasite genetic variability with pathogenesis.

PMID:
12737998
DOI:
10.1016/s1286-4579(03)00050-9
[Indexed for MEDLINE]

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