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Rheumatol Int. 2003 Sep;23(5):262-4. Epub 2003 May 7.

Paraneoplastic eosinophilic fasciitis: a case report.

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1
Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Miami, FL 33125, USA.

Abstract

A 60-year-old white woman with polycythemia rubra vera post splenectomy in November 2001 was found to have peripheral white blood cell counts increasing over 3 months. Cytogenetics revealed trisomy of chromosomes 8 and 9, and bone marrow biopsy showed hypercellular, fibrotic bone marrow consistent with myelofibrosis of polycythemia rubra vera. Two months later, the patient developed acute swelling and pain in her lower extremities. The clinical symptoms along with confirmatory histology supported the diagnosis of eosinophilic fasciitis. This is the first reported case in the English literature of an association between polycythemia vera and eosinophilic fasciitis.

PMID:
12734672
DOI:
10.1007/s00296-003-0317-0
[Indexed for MEDLINE]
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