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Cell Cycle. 2003 May-Jun;2(3):174-6.

The spindle-associated transmembrane protein Axs identifies a new family of transmembrane proteins in eukaryotes.

Author information

1
Stowers Institute for Medical Research, Kansas City, MO 64111, USA.

Abstract

Axs mutations disrupt both the progression of the meiotic cell cycle and meiotic chromosome segregation in Drosophila. Axs protein co-localizes with endoplasmic reticulum components and is present within a novel structure ensheathing the meiotic spindle. We show that Axs encodes the founding member of a eukaryotic family of trans-membrane proteins.

PMID:
12734416
[Indexed for MEDLINE]

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