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Lipids. 2003 Feb;38(2):117-21.

Dietary glycemic index and the regulation of body weight.

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Department of Medicine, Children's Hospital, Boston, Massachusetts 02115, USA.


Prevalence rates of overweight and obesity have risen precipitously in the United States and other developed countries since the 1960s, despite comprehensive public health efforts to combat this problem. Although considerable attention has been focused on decreasing dietary fat and increasing physical activity level, the potential relevance of the dietary glycemic index to obesity treatment has received comparatively little scientific notice. This review examines how the glycemic and insulinemic responses to diet may affect body weight regulation, and argues for the potential utility of low glycemic index diets in the prevention and treatment of obesity and related complications.

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