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Curr Diab Rep. 2003 Apr;3(2):108-14.

Nutrition, growth, and body size in relation to insulin resistance and type 2 diabetes.

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  • 1Diabetes Unit, King Edward Memorial Hospital Research Center, Rasta Peth, Pune 411011, India. diabetes@vsnl.com

Abstract

Nutritional and genetic factors interact in the etiology of type 2 diabetes. Undernutrition followed by overnutrition increases adiposity and the risk of diabetes. The thrifty hypotheses suggest that the nutritional challenges could have happened thousands of year ago (thrifty gene selection) or during one's intrauterine life (thrifty phenotype). Current strategies for the prevention of diabetes are related to avoiding overnutrition.

PMID:
12728636
[PubMed - indexed for MEDLINE]
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