Format

Send to

Choose Destination
Nat Rev Genet. 2003 May;4(5):346-58.

Progress and problems with the use of viral vectors for gene therapy.

Author information

1
Department of Pediatrics, Stanford University School of Medicine, Stanford, California 94305, USA.

Abstract

Gene therapy has a history of controversy. Encouraging results are starting to emerge from the clinic, but questions are still being asked about the safety of this new molecular medicine. With the development of a leukaemia-like syndrome in two of the small number of patients that have been cured of a disease by gene therapy, it is timely to contemplate how far this technology has come, and how far it still has to go.

PMID:
12728277
DOI:
10.1038/nrg1066
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Nature Publishing Group
Loading ...
Support Center