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Nat Rev Mol Cell Biol. 2003 May;4(5):409-14.

Coat proteins: shaping membrane transport.

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1
Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development, Building 18T/Room 101, National Institutes of Health, Bethesda, Maryland 20892, USA.

Abstract

Coat proteins allow the selective transfer of macromolecules from one membrane-enclosed compartment to another by concentrating macromolecules into specialized membrane patches and then deforming these patches into small coated vesicles. Recent findings indicate that coat proteins might also participate in the differentiation of membrane domains within organelles and large transport carriers, as well as in the association of the carriers with the cytosketelon and with acceptor organelles.

PMID:
12728274
DOI:
10.1038/nrm1099
[Indexed for MEDLINE]
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