SCide: identification of stabilization centers in proteins

Zsuzsanna Dosztányi; Csaba Magyar; Gábor Tusnády; István Simon

doi:10.1093/bioinformatics/btg110

SCide: identification of stabilization centers in proteins

Bioinformatics. 2003 May 1;19(7):899-900. doi: 10.1093/bioinformatics/btg110.

Authors

Zsuzsanna Dosztányi¹, Csaba Magyar, Gábor Tusnády, István Simon

Affiliation

¹ Institute of Enzymology Biological Research Center, Hungarian Academy of Sciences, PO Box 7, Budapest, H-1518, Hungary.

PMID: 12724305
DOI: 10.1093/bioinformatics/btg110

Abstract

Summary: SCide is a program to identify stabilization centers from known protein structures. These are residues involved in cooperative long-range contacts, which can be formed between various regions of a single polypeptide chain, or they can belong to different peptides or polypeptides in a complex. The server takes a PDB file as an input, and the result is presented in graphical or text format.

Availability: SCide is available on the web at http://www.enzim.hu/scide. The source code can be obtained from the authors on request.

Publication types

Evaluation Study
Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Binding Sites*
Capsid Proteins / chemistry
Conserved Sequence
Drug Stability*
Information Storage and Retrieval / methods
Molecular Sequence Data
Protein Binding*
Protein Structure, Tertiary
Proteins / chemistry*
Sequence Analysis, Protein / methods*
Software*
Structure-Activity Relationship
User-Computer Interface*

Substances

Capsid Proteins
Proteins
VP2 protein, Foot-and-mouth disease virus