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Mol Cell. 2003 Apr;11(4):846-8.

Closing the GAP: a role for a RhoA GAP in cytokinesis.

Author information

1
Ludwig Institute for Cancer Research, University of California, San Diego, CMM-East 3080, 9500 Gilman Drive, La Jolla 92093, USA.

Abstract

During cell division, cytokinesis partitions the cytoplasm to form two daughter cells. Recently in Developmental Cell, Minoshima et al. (2003) establish an important connection between three regulatory molecules that coordinate this process, showing that the mitotic kinase aurora B phosphorylates MgcRacGAP to convert it to a GAP for RhoA, a small GTPase that drives cytokinesis.

PMID:
12718869
DOI:
10.1016/s1097-2765(03)00151-5
[Indexed for MEDLINE]
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