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Eur Arch Otorhinolaryngol. 2003 Apr;260(4):226-8. Epub 2002 Nov 8.

Recurrent plunging ranula treated with OK-432.

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Department of Otorhinolaryngology and Head and Neck Surgery, Communication Disorder Institute of the Medical Science Research Center, Korea University College of Medicine, Seoul, Korea.


A 36-year-old man was admitted who had a 2-month history of swelling of the right submandibular area and the right side of the mouth floor. He had undergone operations for right plunging ranula with a lesion on the floor of the mouth twice 7 years ago. Under fluoroscopic guidance, the contents of the cyst were aspirated as much as possible and injected with the same amount of OK-432 solution (Picibanil 0.1 mg; 10 ml) twice with 3-week intervals. Examination after 6 weeks showed that the cystic mass seen before therapy had disappeared completely, and no recurrence was encountered after 1 year. We here report a case in which a successful sclerotherapy with OK-432 for recurrent plunging ranula after surgery was performed.

[Indexed for MEDLINE]

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