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Curr Biol. 2003 Apr 15;13(8):R320-2.

Dynactin: coordinating motors with opposite inclinations.

Author information

1
Department of Developmental and Cell Biology, University of California, Irvine, CA 92697, USA. sgross@uci.edu

Abstract

In eukaryotic cells, many organelles are transported bidirectionally along microtubules by kinesin and dynein. These opposite-polarity motors appear to be coordinated to avoid interfering with each other's function. New work has provided the first molecular insight into how such coordination might occur.

PMID:
12699645
[Indexed for MEDLINE]
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