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J Agric Food Chem. 2003 Apr 23;51(9):2520-5.

Functional properties of spice extracts obtained via supercritical fluid extraction.

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1
LASEFI-DEA/FEA-UNICAMP (State University of Campinas), Caixa Postal 6121, 13083-970 Campinas, São Paulo, Brazil.

Abstract

In the present study the antioxidant, anticancer, and antimycobacterial activities of extracts from ginger (Zingiber officinale Roscoe), rosemary (Rosmarinus officinalis L.), and turmeric (Curcuma longa L.) were evaluated. The extracts were obtained using supercritical CO(2) with and without ethanol and/or isopropyl alcohol as cosolvent. The extracts' antioxidant power was assessed using the reaction between beta-carotene and linolenic acid, the antimycobacterial activity against M. tuberculosis was measured by the MABA test, and their anticancer action was tested against nine human cancer ancestries: lung, breast, breast resistant, melanoma, colon, prostate, leukemia, and kidney. The rosemary extracts exhibited the strongest antioxidant and the lowest antimycobacterial activities. Turmeric extracts showed the greatest antimycobacterial activity. Ginger and turmeric extracts showed selective anticancer activities.

PMID:
12696930
DOI:
10.1021/jf0260693
[Indexed for MEDLINE]
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