Malignant glioma physiology: cellular response to hypoxia and its role in tumor progression

Ann Intern Med. 2003 Apr 15;138(8):659-68. doi: 10.7326/0003-4819-138-8-200304150-00014.
No abstract available

Publication types

  • Case Reports
  • Review

MeSH terms

  • Astrocytoma / physiopathology*
  • Astrocytoma / therapy
  • Brain Neoplasms / physiopathology*
  • Brain Neoplasms / therapy
  • Cell Hypoxia
  • DNA-Binding Proteins / physiology
  • Disease Progression
  • Gene Expression Regulation, Neoplastic
  • Glioblastoma / physiopathology
  • Glioblastoma / therapy
  • Humans
  • Hypoxia-Inducible Factor 1
  • Hypoxia-Inducible Factor 1, alpha Subunit
  • Male
  • Middle Aged
  • Neoplasm Invasiveness
  • Neovascularization, Pathologic
  • Nuclear Proteins / physiology
  • Signal Transduction / physiology
  • Transcription Factors*

Substances

  • DNA-Binding Proteins
  • HIF1A protein, human
  • Hypoxia-Inducible Factor 1
  • Hypoxia-Inducible Factor 1, alpha Subunit
  • Nuclear Proteins
  • Transcription Factors