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Dev Cell. 2003 Apr;4(4):449-58.

Patterning systems--from one end of the limb to the other.

Author information

1
Division of Cell and Developmental Biology, School of Life Sciences, University of Dundee, Dundee DD15EH, United Kingdom. c.a.tickle@dundee.ac.uk

Abstract

A combination of embryology and gene identification has led us to the current view of vertebrate limb development, in which a series of three interlocking patterning systems operate sequentially over time. This review describes current understanding of these regulatory mechanisms and how they form a framework for future analysis of limb patterning.

PMID:
12689585
DOI:
10.1016/s1534-5807(03)00095-9
[Indexed for MEDLINE]
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