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Phys Rev Lett. 2003 Mar 28;90(12):128102. Epub 2003 Mar 27.

Pattern formation inside bacteria: fluctuations due to the low copy number of proteins.

Author information

1
Instituut-Lorentz, Leiden University, P.O. Box 9506, 2300 RA Leiden, The Netherlands.

Abstract

We examine fluctuation effects due to the low copy number of proteins involved in pattern-forming dynamics within a bacterium. We focus on a stochastic model of the oscillating MinCDE protein system regulating accurate cell division in E. coli. We find that, for some parameter regions, the protein concentrations are low enough that fluctuations are essential for the generation of patterns. We also examine the role of fluctuations in constraining protein concentration levels.

PMID:
12688905
DOI:
10.1103/PhysRevLett.90.128102
[Indexed for MEDLINE]

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