Format

Send to

Choose Destination
See comment in PubMed Commons below
Appl Environ Microbiol. 2003 Apr;69(4):2365-71.

Heat shock response by the hyperthermophilic archaeon Pyrococcus furiosus.

Author information

  • 1Department of Chemical Engineering, North Carolina State University, Raleigh 27695-7905, USA.

Abstract

Collective transcriptional analysis of heat shock response in the hyperthermophilic archaeon Pyrococcus furiosus was examined by using a targeted cDNA microarray in conjunction with Northern analyses. Differential gene expression suggests that P. furiosus relies on a cooperative strategy of rescue (thermosome [Hsp60], small heat shock protein [Hsp20], and two VAT-related chaperones), proteolysis (proteasome), and stabilization (compatible solute formation) to cope with polypeptide processing during thermal stress.

PMID:
12676722
PMCID:
PMC154833
[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center