Severe transient osteoporosis of the hip during pregnancy. Successful treatment with intravenous biphosphonates

D Schapira; Y Braun Moscovici; G Gutierrez; A M Nahir

Severe transient osteoporosis of the hip during pregnancy. Successful treatment with intravenous biphosphonates

Clin Exp Rheumatol. 2003 Jan-Feb;21(1):107-10.

Authors

D Schapira¹, Y Braun Moscovici, G Gutierrez, A M Nahir

Affiliation

¹ B. Shine Department of Rheumatology, Rambam Medical Center, Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.

PMID: 12673900

Abstract

A young woman with transient osteoporosis of the hip (TOH) during pregnancy, severe pain, physical disability and marked generalized osteoporosis was treated with intravenous biphosphonates with prompt beneficial effects on both clinical symptoms and bone density. The features of this rare and sometimes underdiagnosed condition are reviewed. Intravenous biphosphonates seem to be an effective therapy for TOH.

Publication types

Case Reports

MeSH terms

Absorptiometry, Photon
Adult
Analgesics, Non-Narcotic / administration & dosage
Analgesics, Non-Narcotic / therapeutic use*
Antimetabolites / therapeutic use*
Arthrography
Bone Density / drug effects
Clodronic Acid / administration & dosage
Clodronic Acid / therapeutic use*
Female
Hip Joint* / diagnostic imaging
Hip Joint* / pathology
Humans
Injections, Intravenous
Knee Joint / diagnostic imaging
Knee Joint / pathology
Osteoporosis / drug therapy*
Osteoporosis / etiology
Osteoporosis / pathology
Pregnancy
Pregnancy Complications / drug therapy*
Pregnancy Complications / pathology
Treatment Outcome

Substances

Analgesics, Non-Narcotic
Antimetabolites
Clodronic Acid