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Curr Opin Plant Biol. 2003 Apr;6(2):157-62.

Plant genome modification by homologous recombination.

Author information

1
Institut Supérieur de Biotechnologie de Sfax, route M'harza, 3018. Sfax, Tunisia.

Abstract

The mechanisms and frequencies of various types of homologous recombination (HR) have been studied in plants for several years. However, the application of techniques involving HR for precise genome modification is still not routine. The low frequency of HR remains the major obstacle but recent progress in gene targeting in Arabidopsis and rice, as well as accumulating knowledge on the regulation of recombination levels, is an encouraging sign of the further development of HR-based approaches for genome engineering in plants.

PMID:
12667873
DOI:
10.1016/s1369-5266(03)00016-5
[Indexed for MEDLINE]

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