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Org Lett. 2003 Apr 3;5(7):1031-4.

Facile oxidation of aldehydes to acids and esters with Oxone.

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1
Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, USA.

Abstract

[reaction: see text] A highly efficient, mild, and simple protocol is presented for the oxidation of aldehydes to carboxylic acids utilizing Oxone as the sole oxidant. Direct conversion of aldehydes in alcoholic solvents to their corresponding ester products is also reported. These reactions may prove to be valuable alternatives to traditional metal-mediated oxidations.

PMID:
12659566
DOI:
10.1021/ol0340078
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