Format

Send to

Choose Destination
Int J Syst Evol Microbiol. 2003 Jan;53(Pt 1):289-93.

Chimeric 16S rDNA sequences of diverse origin are accumulating in the public databases.

Author information

1
ComBinE group, Advanced Computational Modelling Centre, The University of Queensland, Brisbane 4072, Australia. philiph@nature.berkeley.edu

Abstract

A significant number of chimeric 16S rDNA sequences of diverse origin were identified in the public databases by partial treeing analysis. This suggests that chimeric sequences, representing phylogenetically novel non-existent organisms, are routinely being overlooked in molecular phylogenetic surveys despite a general awareness of PCR-generated artefacts amongst researchers.

PMID:
12656186
DOI:
10.1099/ijs.0.02441-0
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Ingenta plc
Loading ...
Support Center