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J Am Coll Cardiol. 2003 Mar 19;41(6):1008-12.

The prevalence of coronary artery calcium among diabetic individuals without known coronary artery disease.

Author information

1
Department of Medicine, Section of Cardiology, University of Illinois College of Medicine, 840 S. Wood Street (m/c 715), Chicago, IL 60612, USA. jahoff@uic.edu

Abstract

OBJECTIVES:

We sought to examine the age and gender distribution of coronary artery calcium (CAC) by diabetes status in a large cohort of asymptomatic individuals.

BACKGROUND:

Among individuals with diabetes, coronary artery disease (CAD) is a major cause of morbidity and mortality. Electron-beam tomography (EBT) quantifies CAC, a marker for atherosclerosis.

METHODS:

Screening for CAC by EBT was performed in 30,904 asymptomatic individuals stratified by their self-reported diabetes status, gender, and age. The distribution of CAC across the strata and the association between diabetes and CAC were examined.

RESULTS:

Compared with nondiabetic individuals (n = 29,829), those with diabetes (n = 1,075) had higher median CAC scores across all but two age groups (women 40 to 44 years old and men and women > or =70 years old). Overall, the likelihood of having a CAC score in the highest age/gender quartile was 70% greater for diabetic individuals than for their nondiabetic counterparts.

CONCLUSIONS:

Younger diabetic individuals appear to have calcified plaque burden comparable to that of older individuals without diabetes. These findings call for future research to determine if EBT-CAC screening has an incremental value over the current CAD risk assessment of individuals with diabetes.

PMID:
12651050
[Indexed for MEDLINE]
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