Format

Send to

Choose Destination
Microbes Infect. 2003 Feb;5(2):169-77.

Regulation of antiviral CD8+ T cells by inhibitory natural killer cell receptors.

Author information

1
Department of Pathology and Laboratory Medicine, Woodruff Memorial Research Building, Rm. 7307, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA.

Abstract

Recent evidence indicates that CD8(+) T cells express natural killer cell receptors that constrain the range and magnitude of their activities. For virus-specific CD8(+) T cells, upregulation of these receptors serves to control infection, while concurrently minimizing bystander pathology. Dysregulated expression of these receptors, however, may foster the establishment of persistent virus infection.

PMID:
12650775
DOI:
10.1016/s1286-4579(02)00086-2
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center