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Eur Neurol. 2003;49(3):169-72.

Hypersomnia associated with bilateral posterior hypothalamic lesion. A polysomnographic case study.

Author information

1
Department of Neurology, University of Munich, Munich, Germany. eisen@nefo.med.uni-muenchen.de

Abstract

We examined an obese 58-year-old patient with a bilateral posterior hypothalamic lesion of unknown etiology. A 24-hour polysomnography revealed a markedly increased total sleep time (17.6 h). During daytime, only 3 continuous wake phases occurred. REM periods occurred only between 5 p.m. and 6 a.m. We conclude from our results that, similar to the results from animal experiments, the posterior hypothalamus in humans plays a critical role in the maintenance of wakefulness.

PMID:
12646762
DOI:
10.1159/000069088
[Indexed for MEDLINE]

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