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J Infect. 2003 Apr;46(3):194-6.

Rapidly fatal Haemophilus influenzae serotype f sepsis in a healthy child.

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Medical College of Wisconsin 9000 W. Wisconsin Avenue, Milwaukee, WI, 53226, USA.


A previously healthy 4-year-old child became acutely ill with vomiting and low-grade fever. The following day she suddenly became limp and unresponsive. She experienced acute septic shock and despite aggressive treatment died. Blood cultures grew ampicillin-resistant Haemophilus influenzae type f. There was no evidence of bacterial pneumonia or meningitis. To our knowledge, this represents the first case of fatal H. influenzae type f sepsis in a child without an identifiable focus or underlying predisposing condition. Despite the overwhelming success of the H. influenzae type b vaccine, physicians need to be aware of the potential for severe and fatal H. influenzae infections other than type b.

[Indexed for MEDLINE]

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