Format

Send to

Choose Destination
See comment in PubMed Commons below
Brain Inj. 2003 Apr;17(4):355-8.

Rapid cycling bipolar disorder after left temporal polar damage.

Author information

1
Department of Psychiatry, Faculty of Medicine, Kyoto University, Kyoto, Japan. murai@kuhp.kyoto-u.ac.jp

Abstract

The case of a 48-year-old woman with rapid cycling bipolar disorder subsequent to a traumatic brain injury is reported. Both depressive and manic episodes had an average duration of approximately 1 month, alternating without stable euthymic periods. Neuroradiological examinations revealed a circumscribed lesion in the left temporal pole. After 1 year without treatment, psychiatric intervention and pharmacotherapy was initiated. Her mood swings were successfully treated with the co-administration of valproate and lithium. Case reports of rapid cycling bipolar disorder after traumatic brain injury are very rare and this case supports the idea that temporal polar dysfunction is a candidate for the neurobiological basis of rapid cycling bipolar disorder.

PMID:
12637187
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center