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Annu Rev Neurosci. 2003;26:411-40. Epub 2003 Feb 26.

Molecular approaches to spinal cord repair.

Author information

1
Centre for Research in Neuroscience, McGill University Health Centre, Montreal General Hospital Research Institute, 1650 Cedar Avenue, Montreal, Quebec, Canada, H3G 1A4. sdavid11@po-box.mcgill.ca

Abstract

Axon growth inhibitors associated with myelin and the glial scar contribute to the failure of axon regeneration in the injured adult mammalian central nervous system (CNS). A number of these inhibitors, their receptors, and signaling pathways have been identified. These inhibitors can now be neutralized by a variety of approaches that point to the possibility of developing new therapeutic strategies to stimulate regeneration after spinal cord injury.

[Indexed for MEDLINE]

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