In recent years, employees who complain about too much stress have been increasing, and stressmanagement and coping with stress in the workplace have emerged as one of the important subjects in Occupational Health. There are two approaches to measures for stress. One is to decrease the stressors, and the other is to promote employees' tolerance of the stress reaction. Therefore the roles and duties of Occupational Health Nurses (OHNs) have been described for each approach. OHNs who are close to the employees as first line professionals support each employee to live healthly and independently, and aim at contributing to the employees' QOL. For that reason OHNs' roles in measures for stress must become much more important in the future.