Format

Send to

Choose Destination
Br J Cancer. 2003 Mar 10;88(5):675-8.

Genetic polymorphisms of cytochrome P450 19 and 1B1, alcohol use, and breast cancer risk in Korean women.

Author information

1
Department of Preventive Medicine, Seoul National University College of Medicine, Cancer Research Institute, Chongno-Gu, Seoul, Korea.

Abstract

A case-control study was performed to assess the potential influence of CYP19 Arg(264)Cys and CYP1B1 Leu(432)Val polymorphisms on breast cancer risk in a series of Korean breast cancer patients and controls. The results suggest that the CYP19 Arg(264)Cys polymorphism modifies breast cancer risk (OR=1.5, 95% CI=1.1-2.2), especially in association with alcohol consumption (P for interaction=0.04), whereas the CYP1B1 Leu(432)Val polymorphism appears to play no role here.

PMID:
12618873
PMCID:
PMC2376333
DOI:
10.1038/sj.bjc.6600761
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Nature Publishing Group Icon for PubMed Central
Loading ...
Support Center