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Mech Ageing Dev. 2003 Jan;124(1):9-16.

Systems biology: integrating technology, biology, and computation.

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Institute for Systems Biology, 1441 North 34th Street, Seattle, WA 98103, USA.


The Human Genome Project has changed the worlds of biology and medicine-helping to catalyze two major paradigm changes: systems biology and predictive, preventive and personalized medicine. These two themes will dominate 21st century biology and medicine. I will discuss these changes and indicate how they may interface with with the process of aging.

[Indexed for MEDLINE]

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