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Trends Genet. 2003 Mar;19(3):113-5.

Life after transcription--revisiting the fate of messenger RNA.

Author information

1
Dept of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, St. Paul, MN 55108, USA. khodu001@umn.edu

Abstract

Recently, several groups have used high-density DNA microarrays to study mRNA turnover. These new data suggest that decay contributes significantly to determining mRNA levels, and they should prompt us to refocus our attention on the regulatory potential of mRNA decay.

PMID:
12615000
DOI:
10.1016/S0168-9525(02)00047-1
[Indexed for MEDLINE]
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