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Diagn Microbiol Infect Dis. 2003 Feb;45(2):149-52.

Endocarditis due to glycopeptide-intermediate Staphylococcus aureus: case report and strain characterization.

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Laboratório Especial de Microbiologia Clínica (LEMC), Division of Infectious Diseases, Universidade Federal de Sao Paulo, Sao Paulo, Brazil.


We report a case of infective endocarditis due to vancomycin-intermediate Staphylococcus aureus (VISA) that did not respond to high doses of vancomycin. Initial vancomycin MIC of the last isolate recovered from blood was 8 micro g/mL, but could be induced up to 32 micro g/mL by consecutive growing with vancomycin. Clinical response was only accomplished when linezolid was included in therapy.

[Indexed for MEDLINE]

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