Highly efficient chiral metal cluster systems derived from Ru3(CO)12 and chiral diiminodiphosphines for the asymmetric transfer hydrogenation of ketones

Hui Zhang; Chuan-Bo Yang; Yan-Yun Li; Zhen-Rong Donga; Jing-Xing Gao; Hideaki Nakamura; Kunihiko Murata; Takao Ikariya

doi:10.1039/b209974h

Highly efficient chiral metal cluster systems derived from Ru3(CO)12 and chiral diiminodiphosphines for the asymmetric transfer hydrogenation of ketones

Chem Commun (Camb). 2003 Jan 7:(1):142-3. doi: 10.1039/b209974h.

Authors

Hui Zhang¹, Chuan-Bo Yang, Yan-Yun Li, Zhen-Rong Donga, Jing-Xing Gao, Hideaki Nakamura, Kunihiko Murata, Takao Ikariya

Affiliation

¹ Department of Chemistry, Institute of Physical Chemistry, State Key Laboratory for Physical Chemistry of Solid Surfaces, Xiamen University, Xiamen, 361005 Fujian, China.

PMID: 12611006
DOI: 10.1039/b209974h

Abstract

The chiral Ru cluster-based catalyst systems generated in situ from Ru3(CO)12 and chiral diiminodiphosphine tetradentate ligands effected asymmetric transfer hydrogenation of propiophenone in 2-propanol, leading to 1-phenyl-1-propanol in 94% yield and with 96% ee.