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J Infect Dis. 2003 Feb 15;187(4):691-4. Epub 2003 Jan 29.

Use of an open-reading frame-specific Campylobacter jejuni DNA microarray as a new genotyping tool for studying epidemiologically related isolates.

Author information

1
Department of Microbiology and Immunology, Division of Infectious Diseases, Stanford University, Stanford, California 94305, USA. eleonard@stanford.edu

Abstract

Findings from use of an open-reading frame-specific Campylobacter jejuni DNA microarray to investigate genetic diversity among clinical isolates associated with 5 independent clusters of infection were compared with data from random amplified polymeric DNA (RAPD) and Penner serotyping analyses. The DNA microarray provides a highly specific epidemiological typing tool for analysis of C. jejuni isolates and reveals both divergent and highly conserved gene classes among isolates.

PMID:
12599089
DOI:
10.1086/368268
[Indexed for MEDLINE]

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