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Infect Immun. 2003 Mar;71(3):1566-8.

Role of interleukin-6 in the control of acute and chronic Giardia lamblia infections in mice.

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1
Department of Biology, Georgetown University, Washington, D.C. 20057, USA.

Abstract

In this study, we investigated the role of interleukin-6 (IL-6) in Giardia lamblia infections in mice. Elevated IL-6 expression was found in wild-type mice 15 days postinfection. Furthermore, IL-6-deficient mice controlled infections only slowly although normal immunoglobulin A production was observed. Thus, IL-6 is necessary for early control of acute G. lamblia infections.

PMID:
12595478
PMCID:
PMC148826
[Indexed for MEDLINE]
Free PMC Article
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