Inhalation therapy is the main route of drug administration in patients with obstructive pulmonary diseases. The efficacy of inhalation therapy depends on several factors including the individual choice of the device, its correct use, and patients' compliance. Metered-dose inhalers and dry-powder inhalers require completely different inhalation maneuvers. Poor inhalation technique is associated with poorer disease control. Appropriate education when prescribing inhalation devices and evaluation of inhalation technique are of overwhelming importance.