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Am J Addict. 2002 Fall;11(4):255-61.

Clinical characteristics of under-reporters on urine drug screens in a cocaine treatment study.

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  • 1Medical University of South Carolina, Department of Psychiatry, Center for Drug and Alcohol Programs, 67 President Street, Charleston, SC 29425, USA.


To explore the concordance between urine drug screen (UDS) results and self-report of cocaine use, results in a pharmacologic treatment trial for cocaine dependence were evaluated. Subjects with at least two occurrences of a positive UDS for cocaine were characterized as either an under-reporter (UR, n = 43) or a truthful reporter (TR, n = 32). Interestingly, URs attended more study sessions and were more likely to complete the study. Significant differences were found in cocaine use patterns and the prevalence of Axis I and Axis II disorders. This information may be important in guiding the judicious use of UDS in clinical and research settings.

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