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J Pediatr. 2003 Feb;142(2 Suppl):S21-4; discussion S24-5.

Limitations of maintenance therapy for viral respiratory infection-induced asthma.

Author information

1
Cystic Fibrosis/Respiratory Unit, Department of Child Health, University Hospital of Wales, Cardiff, Wales. doullij@:cf.ac.uk

Abstract

In asthmatic children with persistent symptoms, maintenance therapy with nedocromil sodium, inhaled corticosteroids, or montelukast is associated with a decreased rate of asthma exacerbations. The greatest benefit is seen with use of regular inhaled corticosteroids in preschool- or school-age children, in whom asthma exacerbations, the need for rescue oral corticosteroids, unscheduled urgent medical visits, and hospitalizations are all decreased by approximately 50%. However, maintenance therapy is not beneficial in children with intermittent respiratory virus-induced wheezing without persistent symptoms.

PMID:
12584516
DOI:
10.1067/mpd.2003.22
[Indexed for MEDLINE]

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