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Tropenmed Parasitol. 1976 Mar;27(1):89-92.

Antigen-induced lymphocyte blastogenesis in a hookworm (Necator americanus) infection in man.


A lymphocyte blastogenic technique was employed to examine cell-mediated immunity in a Necator americanus infection. Infective third-stage larvae of N. americanus were jsed for antigen preparation, and lymphocyte cultures were prepared from peripheral blood taken on days 3, 17, and 51 after infection with 250 third-stage larvae of N. americanus. At 3 days post-infection lymphocyte transformation was not induced; at 17 and 51 days after infection significant transformation was obtained.

[Indexed for MEDLINE]

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