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Curr Biol. 2003 Feb 4;13(3):R96-8.

Organogenesis: making pancreas from liver.

Author information

1
Division of Gastroenterology, Hepatology and Nutrition,Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-3039, USA.

Abstract

Making endocrine pancreas cells at will is one of the major goals of cellular based therapies for diabetes. The experimentally induced conversion of hepatocytes into pancreatic cells, using a modified version of the transcription factor Pdx-1, may provide an alternative to stem cell approaches.

PMID:
12573236
DOI:
10.1016/s0960-9822(03)00036-8
[Indexed for MEDLINE]
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