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Heart Lung. 2003 Jan-Feb;32(1):52-8.

A randomized, controlled trial of 1 week of continuous positive airway pressure treatment on quality of life.

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1
Department of Psychiatry, University of California, San Diego, USA.

Abstract

BACKGROUND:

This study examines the effect of continuous positive airway pressure (CPAP) treatment on quality of life (QOL)in patients with obstructive sleep apnea.

METHODS:

Thirty-nine patients with sleep apnea were studied. Health-related quality of life was measured (HRQL) with the use of the Medical Outcomes Survey (MOS) instrument, before and after patients were randomized to receive either 1 week of CPAP or placebo-CPAP (CPAP administered at ineffective pressure).

RESULTS:

CPAP was not found to have a specific effect on QOL as compared with placebo-CPAP. However, several aspects of HRQL improved in both groups over time in this study. Time effects were found in the following subscales of the MOS: satisfaction with physical functioning; effects of pain; pain severity; cognitive functioning; mental health index I; psychological well-being I; depression/behavioral-emotional control; anxiety I; psychological distress I; positive affect II; mental health index II; psychological distress II; anxiety II; psychological well-being II; mental health index III; role limitations due to emotional problems; and physical/physiologic functioning.

CONCLUSIONS:

CPAP treatment does appear to improve several aspects of HRQL. However, this improvement may reflect a nonspecific response (ie, placebo) because comparable improvements were observed in both the active treatment group and the placebo treatment group. Additional study with placebo-CPAP designs is warranted.

PMID:
12571548
DOI:
10.1067/mhl.2003.8
[Indexed for MEDLINE]

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