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Am J Ophthalmol. 2003 Feb;135(2):246-9.

Intravitreal triamcinolone for refractory pseudophakic macular edema.

Author information

1
Department of Ophthalmology, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Université Paris 7, Paris, France. nathanael_benhamou@yahoo.fr

Abstract

PURPOSE:

To evaluate the efficacy of intravitreal triamcinolone in refractory pseudophakic cystoid macular edema.

DESIGN:

A prospective, interventional case series.

METHODS:

Three eyes of three patients with longstanding pseudophakic cystoid macular edema following uncomplicated cataract surgery, refractory to any medication, were treated with 8 mg of intravitreal triamcinolone. All three eyes were evaluated before injection and throughout follow-up with the Early Treatment Diabetic Retinopathy Study's visual acuity chart, fluorescein angiography, and macular mapping using optical coherence tomography.

RESULTS:

A month after intravitreal triamcinolone injection, a dramatic decrease in macular thickness was noted by optical coherence tomography in all three eyes (from a mean of 502-233 microm). Mean improvement in visual acuity was 3.7 Snellen lines. Two to 4 months after triamcinolone injection, however, the edema recurred in all cases, to the same degree as before the injection, combined with a decrease in vision. Two eyes underwent a second injection of triamcinolone, and macular thickness decreased, but the edema again recurred 3 months after injection.

CONCLUSION:

Intravitreal injection of triamcinolone induces striking regression, within 1 month, of chronic refractory macular edema. This regression appears to be transient, however, even after a second injection.

PMID:
12566041
[Indexed for MEDLINE]

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