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Biochem Biophys Res Commun. 2003 Feb 14;301(3):641-5.

Fission yeast synaptobrevin is involved in cytokinesis and cell elongation.

Author information

1
Graduate School of Arts and Sciences, University of Tokyo, Japan. cedam@mail.ecc.u-tokyo.ac.jp

Abstract

Synaptobrevin is a vesicle-associated membrane protein playing an essential role in regulated vesicle transport. In this study, we characterized Syb1, synaptobrevin of Schizosaccharomyces pombe. Syb1 was located on various sizes of vesicle-like structures in the cytoplasm and enriched in the medial region and cell ends. Transport of Syb1 to the medial region was mainly dependent on F-actin and Myo52/Myo4. Syb1 is essential for cell viability and most of the syb1-null cells showed a round or short cylindrical form. These results suggest that Syb1 is involved in membrane trafficking of cytokinesis and cell elongation.

PMID:
12565827
DOI:
10.1016/s0006-291x(03)00017-2
[Indexed for MEDLINE]

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