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Biochem J. 2003 Apr 15;371(Pt 2):233-41.

Regulation of endocytic traffic by Rho GTPases.

Author information

  • 1Department of Neurochemistry and Molecular Biology, Leibniz Institute for Neurobiology, D-39008, Magdeburg, Germany.

Abstract

The members of the Rho subfamily of small GTPases are key regulators of the actin cytoskeleton. However, recent studies have provided evidence for multiple additional roles for these signalling proteins in controlling endocytic traffic. Here we review our current understanding of Rho GTPase action within the endocytic pathway and examine the potential points of convergence with the more established, actin-based functions of these signalling proteins.

PMID:
12564953
PMCID:
PMC1223314
DOI:
10.1042/BJ20030139
[PubMed - indexed for MEDLINE]
Free PMC Article
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