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J Acquir Immune Defic Syndr. 2002 Dec 15;31 Suppl 3:S132-5.

Neurocognitive aspects of medication adherence in HIV infection.

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Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.


Strict adherence to the current highly active antiretroviral therapies (HAART) is a prerequisite for treatment success. The complexities of the treatment regimens places high demands on motivational and cognitive factors, and studies of cognitive predictors of adherence are just beginning to emerge. Traditional measures of new learning and recall may not be among the best neuropsychologic predictors of adherence. Rather, certain aspects of frontal and executive functioning appear to be more strongly associated with good adherence.

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